Indian Journal of Pharmacy and Pharmacology

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Page: 31-36

 Herbs  are  natural  remedies  for  the  disease  with  higher  safety  profile and efficacy .  India  is  gifted  with  varieties  of   large   number  of   medicinal   herbs because  of  variety  of  climatic  conditions  and  seasons  favorable  for  growth of many  species  of  plants.  Amongst the large number of herbal drugs existing in India, very few have been studied systematically so far. Tridax  procumbens  (L) is a highly  valuable  drug  and   is  one  of  the  essential  ingredients in  the  most  of the compound  preparations  included in  Ayurvedic  literature. It is well known for number  of  pharmacological  activities  like   hepatoprotective  activity,   anti-inflammatory,  wound healing,  Antidibetic  activity,  hypotensive  effect,    immunomodulating property, bronchial  catarrh,  dysentery,  diarrhea  and to  prevent  falling of hair, promotes  the  growth  of hair,  and  antimicrobial  activity against both gram-positive and gram-negative bacteria. The leaf  juice  shows  antiseptic,  insecticidal and  parasiticidal   properties,  against  conjunctivitis   and  is   used  also  to  check hemorrhage  from  cuts,  bruises  and   wounds  insect  repellent.  It is also used as bioadsorbent for chromium. Here we try to make attempt for focusing on antimicrobial activity of Tridax procumbens flowers.  Their antibacterial activities were evaluated in vitro against clinical bacterial isolates.  In effort to identify novel bacterial agents, this study was initiated to evaluate the antimicrobial properties of Tridax procumbens flowers extract against E. coli and Staphylococcus aureus by using disc-diffusion assay.  The flower plant extracts demonstrated good antimicrobial activity against these bacteria tested with inhibition zones. The minimal inhibitory concentration (MIC) values of extract against the tested bacteria were found to 67.3 mg/ml and 48.20 against E.coli and Staphylococcus aureus respectively. The methanolic extract of flowers exhibited a pronounced activity against E. coli and Staphylococcus aureus.  The minimum inhibitory concentration was found in methanolic Extracts of Tridax procumbens against test organisms.